1
00:00:04,810 --> 00:00:06,386
I don't get it.

2
00:00:06,410 --> 00:00:08,656
Glowing chest... what does that mean?

3
00:00:08,680 --> 00:00:10,086
It's not a riddle.

4
00:00:10,110 --> 00:00:11,540
I have a glowing chest.

5
00:00:11,650 --> 00:00:13,526
Those two words

6
00:00:13,550 --> 00:00:15,956
don't belong together. Chests don't glow.

7
00:00:15,980 --> 00:00:18,096
But they can glow.

8
00:00:18,120 --> 00:00:20,426
See, I gave myself a
treatment called crispr.

9
00:00:20,450 --> 00:00:22,850
"Clustered regularly inter spaced

10
00:00:22,960 --> 00:00:25,560
short palindromic repeats."

11
00:00:26,360 --> 00:00:28,876
It hacks your DNA. Changes your genes.

12
00:00:28,900 --> 00:00:30,900
You can make your body different.

13
00:00:31,030 --> 00:00:34,216
You can make it better.
You can make it glow.

14
00:00:34,240 --> 00:00:35,376
Why, though?

15
00:00:35,400 --> 00:00:36,876
Glowing chest.

16
00:00:36,900 --> 00:00:39,946
There is a longer answer.

17
00:00:39,970 --> 00:00:42,570
Divorce, general lack of purpose.

18
00:00:42,680 --> 00:00:46,386
The human need to
pursue something, anything,

19
00:00:46,410 --> 00:00:49,710
even a glowing chest.
Especially a glowing chest.

20
00:00:49,820 --> 00:00:50,990
Are you lying?

21
00:00:58,760 --> 00:01:00,066
Glowing chest.

22
00:01:01,500 --> 00:01:03,206
There was someone in here earlier,

23
00:01:03,230 --> 00:01:04,676
had a fork stuck to her fingers.

24
00:01:04,700 --> 00:01:07,416
Neodymium magnetic implants.

25
00:01:07,440 --> 00:01:10,976
Technically, it's a body
mod, not a gene hack,

26
00:01:11,000 --> 00:01:12,900
but we're all part of the same community.

27
00:01:13,010 --> 00:01:14,656
And is that legal?

28
00:01:14,680 --> 00:01:17,656
The law is... Still
catching up to what we do.

29
00:01:17,680 --> 00:01:19,056
Hobie?

30
00:01:19,080 --> 00:01:21,426
Wendy. Hi.

31
00:01:21,450 --> 00:01:22,756
Hi.

32
00:01:23,950 --> 00:01:25,250
Sorry, that was...

33
00:01:26,120 --> 00:01:28,720
okay.

34
00:01:29,990 --> 00:01:33,566
It's so nice to meet you in person.

35
00:01:33,590 --> 00:01:35,806
You look exactly like you do on chat.

36
00:01:35,830 --> 00:01:37,400
You look better.

37
00:01:38,270 --> 00:01:41,110
Do-do you want to sit? I got us a table.

38
00:01:41,240 --> 00:01:42,916
Yeah, we could.

39
00:01:42,940 --> 00:01:44,840
Or...

40
00:01:46,170 --> 00:01:48,140
we could get room service.

41
00:01:58,750 --> 00:02:01,320
You went all out.

42
00:02:02,420 --> 00:02:03,796
What if you weren't attracted to me?

43
00:02:03,820 --> 00:02:05,790
I wasn't worried.

44
00:02:07,630 --> 00:02:10,676
Hobie McSorley from Pittsburgh.

45
00:02:10,700 --> 00:02:13,270
Wendy goss from utica.

46
00:02:14,740 --> 00:02:16,746
Are you sure you want to do this?

47
00:02:16,770 --> 00:02:18,916
I mean, body mods are one thing.

48
00:02:18,940 --> 00:02:21,480
We're talking about
getting into your genome.

49
00:02:21,610 --> 00:02:22,786
I'm sure.

50
00:02:22,810 --> 00:02:24,510
I want my first time to be with you.

51
00:02:24,650 --> 00:02:28,296
Okay, this might be weird,
and it's definitely too soon,

52
00:02:28,320 --> 00:02:31,850
but... I think I want to say "I love you."

53
00:02:32,950 --> 00:02:36,490
Well, it's not any weirder
than what we're about to do.

54
00:02:37,930 --> 00:02:39,500
I love you too, hobie.

55
00:02:40,660 --> 00:02:42,500
Put it in me.

56
00:03:04,290 --> 00:03:07,166
It's working.

57
00:03:11,890 --> 00:03:13,506
Yours should appear any second.

58
00:03:13,530 --> 00:03:15,070
Okay.

59
00:03:23,570 --> 00:03:25,310
Maybe we should kiss.

60
00:03:26,640 --> 00:03:27,940
- Yeah.
- Yeah.

61
00:03:29,310 --> 00:03:30,440
Yeah.

62
00:03:35,080 --> 00:03:37,380
I'm sorry, hobie. I don't feel so great.

63
00:03:37,490 --> 00:03:39,496
What?

64
00:03:39,520 --> 00:03:42,560
- You okay?
- No.

65
00:03:43,820 --> 00:03:45,636
Wendy?

66
00:04:00,210 --> 00:04:02,080
Sorry to interrupt.

67
00:04:02,210 --> 00:04:03,586
It's the end of the day, shinwell.

68
00:04:03,610 --> 00:04:04,856
I think, at the end of the day...

69
00:04:04,880 --> 00:04:06,626
- I am aware of this.
- Ten minutes.

70
00:04:06,650 --> 00:04:08,496
Ten minutes to review our cases

71
00:04:08,520 --> 00:04:10,656
and think about next steps.
It's not an enormous ask.

72
00:04:10,680 --> 00:04:13,420
No, it's... it's an entirely reasonable ask.

73
00:04:14,420 --> 00:04:17,566
But I do wonder if, perhaps,
on this particular evening,

74
00:04:17,590 --> 00:04:21,936
your ten minutes can
perhaps wait ten minutes?

75
00:04:21,960 --> 00:04:23,406
It's the fellows.

76
00:04:23,430 --> 00:04:25,876
They're struggling a
bit with the transplant.

77
00:04:25,900 --> 00:04:28,116
Okay, first, somebody's
gonna have to pick up the snot

78
00:04:28,140 --> 00:04:29,480
and put it in the fridge.

79
00:04:29,600 --> 00:04:30,916
Snot transplant.

80
00:04:30,940 --> 00:04:32,416
- I don't like it. Sounds fake.
- It's real.

81
00:04:32,440 --> 00:04:33,516
We're doing it tomorrow.

82
00:04:33,540 --> 00:04:35,070
Remind me how we picked the donor.

83
00:04:35,180 --> 00:04:37,486
By the quality of her snot, obviously.

84
00:04:37,510 --> 00:04:38,510
Which is measured how?

85
00:04:38,610 --> 00:04:39,950
Okay, enough.

86
00:04:40,080 --> 00:04:43,096
Laine sudow has had
sinus infections her entire life.

87
00:04:43,120 --> 00:04:46,096
Tomorrow, we swap out her
bad snot for the good snot.

88
00:04:46,120 --> 00:04:47,636
Problem solved.

89
00:04:47,660 --> 00:04:51,700
But first, someone has
to preserve the specimen.

90
00:04:55,600 --> 00:04:57,706
Y'all are such wimps.

91
00:04:59,770 --> 00:05:02,046
Thank you, Dr. Lubbock.

92
00:05:02,070 --> 00:05:03,216
Where are you going?

93
00:05:03,240 --> 00:05:04,840
To think.

94
00:05:06,440 --> 00:05:08,156
John, you're still here. Good.

95
00:05:08,180 --> 00:05:09,656
My body's still here.

96
00:05:09,680 --> 00:05:11,680
My brain is looking for
someplace way far away.

97
00:05:11,810 --> 00:05:14,056
I was going to ask you for a favor,

98
00:05:14,080 --> 00:05:16,496
but if you're in your
special selfish genius place,

99
00:05:16,520 --> 00:05:17,626
- it can wait.
- I don't have a special

100
00:05:17,650 --> 00:05:19,520
selfish genius place.

101
00:05:19,650 --> 00:05:21,250
What is it?

102
00:05:22,090 --> 00:05:23,490
I won an award.

103
00:05:23,620 --> 00:05:26,466
The deltas are honoring
me for my work in the clinics.

104
00:05:26,490 --> 00:05:28,220
I say a few words, I get a plaque,

105
00:05:28,330 --> 00:05:30,676
my picture goes on the wall.

106
00:05:30,700 --> 00:05:31,870
Wow, the deltas.

107
00:05:32,000 --> 00:05:33,746
That's huge. Congratulations.

108
00:05:33,770 --> 00:05:36,116
Someone has to introduce me.

109
00:05:36,140 --> 00:05:39,586
They talk about my work,
my volunteer commitments,

110
00:05:39,610 --> 00:05:40,810
my good qualities.

111
00:05:42,640 --> 00:05:44,070
Someone...

112
00:05:45,680 --> 00:05:46,756
Do I need to fill in the blanks?

113
00:05:46,780 --> 00:05:48,856
So you want me to
give a speech about you.

114
00:05:48,880 --> 00:05:51,680
About my professional and
philanthropic achievements.

115
00:05:51,820 --> 00:05:53,626
You can leave the other stuff out.

116
00:05:53,650 --> 00:05:55,566
I'm gonna ask Dr. Kim.

117
00:05:55,590 --> 00:05:57,536
Okay, no, look, I will do it.

118
00:05:57,560 --> 00:05:58,966
Of course I'll do it.

119
00:05:58,990 --> 00:06:00,166
Give me the time,
place and the dress code,

120
00:06:00,190 --> 00:06:01,560
and I'll be there.

121
00:06:01,700 --> 00:06:03,376
Thank you.

122
00:06:03,400 --> 00:06:06,546
John, I have to submit the
introduction ahead of time.

123
00:06:06,570 --> 00:06:08,716
Two minutes or so. Get it
to me two days from now?

124
00:06:08,740 --> 00:06:10,410
You got it.

125
00:06:52,080 --> 00:06:53,280
Sherlock?

126
00:06:55,920 --> 00:06:57,820
Watson.

127
00:06:59,920 --> 00:07:01,590
I was hoping to surprise you.

128
00:07:01,720 --> 00:07:03,666
You've been sleeping
in the abandoned wing?

129
00:07:03,690 --> 00:07:06,290
Just the past couple nights.

130
00:07:07,430 --> 00:07:08,606
We've had worse, my friend.

131
00:07:08,630 --> 00:07:09,760
Yeah, but why?

132
00:07:11,700 --> 00:07:13,430
It's under there, Watson.

133
00:07:17,670 --> 00:07:19,770
Awaiting the grand unveiling.

134
00:07:20,940 --> 00:07:22,916
What's under there?

135
00:07:22,940 --> 00:07:26,756
In 1929, the markets crashed.

136
00:07:26,780 --> 00:07:30,226
The prairies turned to dust
and your country starved.

137
00:07:30,250 --> 00:07:31,926
I know about the great depression.

138
00:07:31,950 --> 00:07:33,266
And did you know that your government,

139
00:07:33,290 --> 00:07:35,396
in an effort to keep people working,

140
00:07:35,420 --> 00:07:37,520
commissioned a series of public murals

141
00:07:37,630 --> 00:07:39,330
by the great artists of the day?

142
00:07:40,090 --> 00:07:43,306
Some are as good as
new. Others have been lost.

143
00:07:43,330 --> 00:07:45,106
That wall, John.

144
00:07:45,130 --> 00:07:48,846
A mural by the late Charles alston

145
00:07:48,870 --> 00:07:51,310
under the paint there.

146
00:07:52,270 --> 00:07:54,740
Looks like a wall, Holmes.

147
00:07:55,780 --> 00:07:58,456
Well, you have to look deeper, Watson.

148
00:07:58,480 --> 00:07:59,920
It's a miracle.

149
00:08:00,850 --> 00:08:04,780
A masterpiece, waiting to be uncovered.

150
00:08:09,820 --> 00:08:10,990
Holmes.

151
00:08:12,830 --> 00:08:14,830
You have to look deeper, Watson.

152
00:08:14,960 --> 00:08:16,190
It's a miracle.

153
00:08:16,330 --> 00:08:19,646
A masterpiece, waiting to be uncovered.

154
00:08:19,670 --> 00:08:21,170
You just said that.

155
00:08:22,700 --> 00:08:23,816
Did I? I don't think so.

156
00:08:23,840 --> 00:08:25,846
No, yeah, you did.

157
00:08:25,870 --> 00:08:27,540
Look, whatever this is,

158
00:08:27,680 --> 00:08:29,856
let's go back to my place
and talk about it, okay?

159
00:08:31,280 --> 00:08:32,986
Hobie, I'm a little busy right now.

160
00:08:33,010 --> 00:08:36,056
John, I need your help,
John. I need your help now!

161
00:08:36,080 --> 00:08:37,096
What's going on?

162
00:08:37,120 --> 00:08:39,896
It's Wendy. She's my...

163
00:08:39,920 --> 00:08:41,496
I don't know, I don't know. We were...

164
00:08:41,520 --> 00:08:43,136
We were doing a crispr mod together,

165
00:08:43,160 --> 00:08:45,936
and I was careful. I
promise I was so careful.

166
00:08:45,960 --> 00:08:47,860
Calm down. Tell me what happened.

167
00:08:48,000 --> 00:08:50,376
I love her. I mean, I think I love her.

168
00:08:50,400 --> 00:08:52,246
I told her I love her.

169
00:08:52,270 --> 00:08:54,676
I'm in love with Wendy, Watson.

170
00:08:54,700 --> 00:08:57,570
And I'm worried maybe I killed her.

171
00:09:16,220 --> 00:09:19,120
Incoming. Room 3 is empty.

172
00:09:20,530 --> 00:09:24,076
Wendy. Wendy, I'm
Dr. Marcus. Can you hear me?

173
00:09:24,100 --> 00:09:26,170
Wendy goss. Are you with us, Wendy?

174
00:09:27,600 --> 00:09:29,516
You warned me.

175
00:09:29,540 --> 00:09:30,900
You warned me over and over again.

176
00:09:30,940 --> 00:09:32,416
Send a stat cbc and a chem 7.

177
00:09:32,440 --> 00:09:33,916
You told me that if I
kept playing with DNA,

178
00:09:33,940 --> 00:09:35,686
something bad was
gonna happen, but I thought

179
00:09:35,710 --> 00:09:36,856
you meant me, you know?
I didn't care about myself.

180
00:09:36,880 --> 00:09:38,256
I mean, not then, anyhow.

181
00:09:38,280 --> 00:09:39,786
Okay, hobie, you can
beat yourself up later.

182
00:09:39,810 --> 00:09:41,226
I need to know what you two were doing

183
00:09:41,250 --> 00:09:42,596
in that hotel room.

184
00:09:42,620 --> 00:09:44,556
It was the first time
that we met in person,

185
00:09:44,580 --> 00:09:46,096
and we wanted to make it special,

186
00:09:46,120 --> 00:09:47,696
so I-I worked up a love mod.

187
00:09:47,720 --> 00:09:48,766
What's a love mod?

188
00:09:48,790 --> 00:09:50,490
It's a riff on the bio hack

189
00:09:50,620 --> 00:09:52,136
I used to make my chest glow,

190
00:09:52,160 --> 00:09:55,006
except using bioluminescence
from red mushroom coral.

191
00:09:55,030 --> 00:09:56,676
Me and Wendy... we
were supposed to get

192
00:09:56,700 --> 00:09:58,246
matching glowing hearts,

193
00:09:58,270 --> 00:10:00,606
but only when we were
together and, you know, feeling...

194
00:10:00,630 --> 00:10:01,946
Love.

195
00:10:01,970 --> 00:10:04,540
You just met tonight.
How could you be in love?

196
00:10:05,670 --> 00:10:07,086
Forget that. We'll talk about that later.

197
00:10:07,110 --> 00:10:08,956
So, if I'm hearing you right, this glow...

198
00:10:08,980 --> 00:10:10,310
it's triggered by oxytocin.

199
00:10:10,440 --> 00:10:11,686
The love hormone.

200
00:10:11,710 --> 00:10:12,786
Okay, what about the heart shape?

201
00:10:12,810 --> 00:10:14,540
They're tattoos, just using

202
00:10:14,650 --> 00:10:15,996
my gene cassette instead of ink.

203
00:10:16,020 --> 00:10:18,490
I-I mailed Wendy the serum so that

204
00:10:18,620 --> 00:10:20,996
we could get tattooed in time for her visit.

205
00:10:21,020 --> 00:10:22,666
The injection at the
hotel... it was just a booster.

206
00:10:22,690 --> 00:10:25,336
It-it was Wendy's first
time messing with crispr.

207
00:10:25,360 --> 00:10:27,360
She trusted me, Watson.

208
00:10:27,490 --> 00:10:29,636
I know. Yeah, I know she did. Listen,

209
00:10:29,660 --> 00:10:32,146
Wendy is my patient now.
We're gonna do everything we can

210
00:10:32,170 --> 00:10:35,040
to bail you out of this. I
need a sample of the serum,

211
00:10:35,170 --> 00:10:37,316
the booster, your whole full schematic.

212
00:10:37,340 --> 00:10:38,916
Wait, bail me out? What do you mean?

213
00:10:38,940 --> 00:10:41,246
- Am i-am I in trouble?
- Your girlfriend is sick, hobie.

214
00:10:41,270 --> 00:10:44,086
You injected her with something
you cooked up in your garage,

215
00:10:44,110 --> 00:10:45,240
and she's sick.

216
00:10:45,350 --> 00:10:46,656
Now, are you in trouble? I don't know.

217
00:10:46,680 --> 00:10:50,250
If we can't make her
better... I don't know.

218
00:10:55,120 --> 00:10:59,166
Wendy goss. She's in the
icu now with hemolytic anemia.

219
00:10:59,190 --> 00:11:01,730
Her red blood cells are
popping like balloons.

220
00:11:01,860 --> 00:11:04,360
So far, her kidneys are unaffected.

221
00:11:04,500 --> 00:11:07,070
Let's focus on finding the cause.

222
00:11:07,200 --> 00:11:08,616
It's the tattoo.

223
00:11:08,640 --> 00:11:10,176
Innit?

224
00:11:10,200 --> 00:11:14,016
In my observations, I have observed

225
00:11:14,040 --> 00:11:17,580
that a couple's tattoo is
the surest path to suffering.

226
00:11:17,710 --> 00:11:19,486
I didn't mean the Karma cause.

227
00:11:19,510 --> 00:11:20,856
I was looking for the medical cause.

228
00:11:20,880 --> 00:11:22,226
Could be infection.

229
00:11:22,250 --> 00:11:24,626
Her body mods put her at higher risk.

230
00:11:24,650 --> 00:11:26,750
Or an immune-driven food allergy.

231
00:11:26,890 --> 00:11:29,466
Okay, good. Good. Let's
test her antibody level

232
00:11:29,490 --> 00:11:30,796
and start antibiotics.

233
00:11:30,820 --> 00:11:32,920
Sorry, this woman mainlined

234
00:11:33,060 --> 00:11:34,976
a garage juice crispr cocktail,

235
00:11:35,000 --> 00:11:36,706
and we're worried about allergies?

236
00:11:36,730 --> 00:11:38,576
We need to consider
everything, Dr. Derian,

237
00:11:38,600 --> 00:11:40,076
but that is a fair point.

238
00:11:40,100 --> 00:11:41,876
Wendy is a bio hacker.

239
00:11:41,900 --> 00:11:43,476
She's been experimenting with

240
00:11:43,500 --> 00:11:45,600
mechanical additions and implants.

241
00:11:45,740 --> 00:11:48,356
Hobie's love mod is the first time

242
00:11:48,380 --> 00:11:49,620
she messed with her own genome.

243
00:11:49,740 --> 00:11:51,440
So this could be genetic instability.

244
00:11:51,580 --> 00:11:52,920
The labs are gonna tell us more,

245
00:11:53,050 --> 00:11:55,956
but for now, let's
explore if Wendy's issues

246
00:11:55,980 --> 00:11:59,626
come from her body
mods or hobie's shot.

247
00:11:59,650 --> 00:12:00,996
Sasha and Stephens,

248
00:12:01,020 --> 00:12:03,566
hit the lab. Check the
serum and Wendy's DNA,

249
00:12:03,590 --> 00:12:07,736
especially the sequence
that was targeted by that mod.

250
00:12:07,760 --> 00:12:10,300
Ingrid and Adam, go to Wendy's hotel,

251
00:12:10,430 --> 00:12:11,746
dig through all of her stuff.

252
00:12:11,770 --> 00:12:13,946
See what else we can
learn about these mods.

253
00:12:13,970 --> 00:12:17,016
Dr. Watson, did you, by chance,

254
00:12:17,040 --> 00:12:20,840
invite the Pittsburgh police this evening?

255
00:12:24,480 --> 00:12:27,526
Detective lestrade. To
what do I owe the pleasure?

256
00:12:27,550 --> 00:12:28,956
Evening, good looking.

257
00:12:28,980 --> 00:12:31,526
How do you keep your
suit so perky after sundown?

258
00:12:31,550 --> 00:12:34,226
Maybe I sweat starch.
Maybe I don't sweat at all.

259
00:12:34,250 --> 00:12:36,750
- How can I be of service?
- Not here to see you.

260
00:12:36,860 --> 00:12:38,590
I need a word with Dr. Lubbock.

261
00:12:39,730 --> 00:12:42,106
Me? Is everything okay?

262
00:12:42,130 --> 00:12:44,300
Is there a private place we could talk?

263
00:12:48,770 --> 00:12:49,810
He's dead?

264
00:12:49,940 --> 00:12:52,146
Uncle jun is dead?

265
00:12:52,170 --> 00:12:54,316
A neighbor called in a wellness check.

266
00:12:54,340 --> 00:12:56,516
We found him lying in bed.

267
00:12:56,540 --> 00:12:58,656
There were a couple of
beer cans scattered around.

268
00:12:58,680 --> 00:13:01,486
I recognized a photograph
of you on the nightstand.

269
00:13:01,510 --> 00:13:03,156
You called him uncle jun?

270
00:13:03,180 --> 00:13:05,896
What was the nature
of your relationship?

271
00:13:05,920 --> 00:13:07,696
It's just how he introduced himself.

272
00:13:07,720 --> 00:13:09,496
He said he was my uncle.

273
00:13:09,520 --> 00:13:12,006
He said that, he knew my birth mom.

274
00:13:12,030 --> 00:13:13,336
But the whole approach was a lie.

275
00:13:13,360 --> 00:13:17,536
He was just looking
for someone to talk to.

276
00:13:17,560 --> 00:13:18,806
What happened to him?

277
00:13:18,830 --> 00:13:20,346
We don't know yet.

278
00:13:20,370 --> 00:13:22,240
There were certain signs.

279
00:13:23,040 --> 00:13:24,746
You think he did this to himself?

280
00:13:24,770 --> 00:13:26,786
We have to wait for the toxicology report

281
00:13:26,810 --> 00:13:29,010
to get back, but, there's
a gray area between

282
00:13:29,140 --> 00:13:31,826
doing it to yourself and letting it happen.

283
00:13:31,850 --> 00:13:33,690
We call that a death of despair.

284
00:13:34,480 --> 00:13:36,596
This kind of feels like that.

285
00:13:36,620 --> 00:13:38,720
You hadn't spoken to jun recently?

286
00:13:38,850 --> 00:13:40,326
Not for a while.

287
00:13:40,350 --> 00:13:43,220
Not since I figured
out he was lying to me.

288
00:13:44,390 --> 00:13:45,966
He died alone?

289
00:13:45,990 --> 00:13:47,520
I'm afraid he did.

290
00:13:48,560 --> 00:13:51,760
It's a sad situation, but this
is not your fault, Dr. Lubbock.

291
00:13:52,700 --> 00:13:55,870
If you're interested, I could
let you know what I learn.

292
00:14:09,680 --> 00:14:11,550
This is a hospital room, not a crypt.

293
00:14:12,350 --> 00:14:14,550
Well, I'm trying to
make up for the fact that

294
00:14:14,690 --> 00:14:16,696
our first date ended up in the icu.

295
00:14:16,720 --> 00:14:18,220
Hobie, you told the triage nurse

296
00:14:18,330 --> 00:14:20,106
that Wendy had an RFID chip

297
00:14:20,130 --> 00:14:22,206
made of bio glass in
the back of each hand.

298
00:14:22,230 --> 00:14:24,706
We haven't seen any
sign of infection there.

299
00:14:24,730 --> 00:14:27,146
Are there any other body mods
that we should know about?

300
00:14:27,170 --> 00:14:29,516
The finger magnets. And she has

301
00:14:29,540 --> 00:14:32,246
a transmitter in her
ribcage. Wendy told me

302
00:14:32,270 --> 00:14:34,016
that it was supposed to
send her body temperature

303
00:14:34,040 --> 00:14:35,940
to her thermostat.

304
00:14:36,080 --> 00:14:37,416
There were complications.

305
00:14:37,440 --> 00:14:39,456
Okay, so we'll test for metal toxicity.

306
00:14:39,480 --> 00:14:41,326
We'll also measure her cytokine levels.

307
00:14:41,350 --> 00:14:43,090
Okay.

308
00:14:43,950 --> 00:14:45,680
She's jaundiced.

309
00:14:47,590 --> 00:14:49,130
Looks like her anemia's getting worse.

310
00:14:49,260 --> 00:14:51,736
Half my team is looking
over her labs, the other half

311
00:14:51,760 --> 00:14:53,166
is digging through that hotel room.

312
00:14:53,190 --> 00:14:54,460
We'll know something soon.

313
00:14:54,590 --> 00:14:57,870
- Okay.
- But hobie, why did you do this?

314
00:14:59,300 --> 00:15:00,300
Love.

315
00:15:00,430 --> 00:15:01,800
I wish you'd stop saying that.

316
00:15:01,940 --> 00:15:04,676
You can't love someone
you met five hours ago.

317
00:15:04,700 --> 00:15:05,646
You disagree?

318
00:15:05,670 --> 00:15:07,686
I disagree because you're wrong.

319
00:15:07,710 --> 00:15:11,150
Judge what we did, what I did, but

320
00:15:11,280 --> 00:15:12,950
don't tell me who I can love.

321
00:15:14,050 --> 00:15:16,150
You're not that good of a doctor.

322
00:15:27,190 --> 00:15:29,236
It looks like a hallmark
card threw up in here.

323
00:15:29,260 --> 00:15:32,476
No visible signs of mold or pesticides.

324
00:15:32,500 --> 00:15:34,670
I'll check for moisture. You
want to check the fridge?

325
00:15:38,310 --> 00:15:39,540
You okay?

326
00:15:41,740 --> 00:15:43,180
Ingrid, you're staring.

327
00:15:43,310 --> 00:15:45,956
Nothing's gonna...

328
00:15:45,980 --> 00:15:47,956
Happen here. You realize that, right?

329
00:15:47,980 --> 00:15:50,480
Happen? Ew. What could possibly

330
00:15:50,620 --> 00:15:52,126
make you think that
something might happen?

331
00:15:52,150 --> 00:15:53,796
We're in a hotel room
and you're staring at me.

332
00:15:53,820 --> 00:15:56,366
I'm not staring at you, I'm judging you.

333
00:15:56,390 --> 00:15:58,566
I'm deciding if I want
to tell you something.

334
00:15:58,590 --> 00:16:01,330
Okay.

335
00:16:02,330 --> 00:16:04,030
What is it?

336
00:16:04,160 --> 00:16:06,476
I'm in the middle of a situation

337
00:16:06,500 --> 00:16:08,176
that might not be so great.

338
00:16:08,200 --> 00:16:10,976
I can't talk to anybody about it
because they'd have opinions.

339
00:16:11,000 --> 00:16:13,300
You're kind of a blank slate...

340
00:16:13,410 --> 00:16:16,916
human void, if you will...
so you might be safe.

341
00:16:16,940 --> 00:16:18,780
That is so sweet.

342
00:16:19,850 --> 00:16:23,796
Remember Beck? Beck
wythe, like "lithe" but with a "w"?

343
00:16:23,820 --> 00:16:25,526
You mean the guy who
stabbed a man in the neck

344
00:16:25,550 --> 00:16:27,926
with a pair of scissors right by my desk?

345
00:16:27,950 --> 00:16:29,666
I do remember him. Yes.

346
00:16:29,690 --> 00:16:32,036
I go over to his place sometimes.

347
00:16:32,060 --> 00:16:33,866
We take off our clothes.
That kind of thing.

348
00:16:33,890 --> 00:16:35,606
And are you asking
me if you should stop?

349
00:16:35,630 --> 00:16:37,506
Because you should definitely stop.

350
00:16:37,530 --> 00:16:40,506
I know what Beck is.

351
00:16:40,530 --> 00:16:42,146
In fact, I hold him in contempt.

352
00:16:42,170 --> 00:16:48,040
But there is one specific
thing that he's very good at.

353
00:16:49,540 --> 00:16:52,526
In my head, there are compartments.

354
00:16:52,550 --> 00:16:56,726
And in one drawer is who Beck is,

355
00:16:56,750 --> 00:16:58,926
in the other drawer is what Beck does.

356
00:16:58,950 --> 00:17:00,520
They're the same drawer.

357
00:17:01,350 --> 00:17:02,720
Sasha guessed it.

358
00:17:03,890 --> 00:17:05,406
I told her I'd stop.

359
00:17:05,430 --> 00:17:07,400
I do feel bad about that.

360
00:17:07,530 --> 00:17:08,800
You've come a long way.

361
00:17:09,500 --> 00:17:12,240
Not nearly far enough, but still.

362
00:17:13,000 --> 00:17:15,440
I'll break this down for you. There's you.

363
00:17:16,600 --> 00:17:17,846
You're a mess.

364
00:17:17,870 --> 00:17:21,486
Dangerous at times,
but still, you know, Ingrid.

365
00:17:21,510 --> 00:17:24,556
And over here, there's Beck.

366
00:17:24,580 --> 00:17:26,756
And he is something different altogether.

367
00:17:26,780 --> 00:17:28,896
I don't care if you guys go
to the same therapy group

368
00:17:28,920 --> 00:17:31,256
or if you have the same
diagnosis or whatever.

369
00:17:31,280 --> 00:17:35,080
I was locked in a room with
a man strapped to a bomb

370
00:17:35,220 --> 00:17:37,050
and with Beck.

371
00:17:37,160 --> 00:17:39,130
Beck scared me more.

372
00:17:39,930 --> 00:17:40,906
End this.

373
00:17:40,930 --> 00:17:43,330
Don't overestimate yourself.

374
00:17:50,100 --> 00:17:51,716
She has chikke'en in her fridge.

375
00:17:51,740 --> 00:17:54,316
Didn't hobie say that Wendy was vegan?

376
00:17:54,340 --> 00:17:56,786
No, not chicken.

377
00:17:56,810 --> 00:17:58,350
Chikke'en with two ks.

378
00:17:59,150 --> 00:18:00,786
Does it make a difference?

379
00:18:00,810 --> 00:18:02,056
I don't know.

380
00:18:02,080 --> 00:18:03,820
I'm gonna text Watson the ingredients.

381
00:18:15,130 --> 00:18:16,136
Sherlock.

382
00:18:20,870 --> 00:18:23,370
Were you watching me?

383
00:18:24,170 --> 00:18:26,000
What's going on with you, Holmes?

384
00:18:26,110 --> 00:18:28,786
I don't just mean the
camping out at the hospital.

385
00:18:28,810 --> 00:18:30,616
I mean the faking your own death,

386
00:18:30,640 --> 00:18:33,510
disappearing acts, the paranoia.

387
00:18:33,650 --> 00:18:36,050
Spray-painting the walls at my hospital.

388
00:18:37,550 --> 00:18:38,890
What's going on?

389
00:18:40,150 --> 00:18:42,196
I've been thinking about dying, John.

390
00:18:42,220 --> 00:18:43,566
I'll be gone

391
00:18:43,590 --> 00:18:45,666
soon enough. We'll all
be gone soon enough.

392
00:18:45,690 --> 00:18:50,406
But right now, today,
here, on your couch,

393
00:18:50,430 --> 00:18:52,406
my mind still works.

394
00:18:52,430 --> 00:18:54,806
Now, look, I could solve crimes

395
00:18:54,830 --> 00:18:56,630
until I keel over, and I'm not saying

396
00:18:56,740 --> 00:18:58,110
that's time wasted.

397
00:18:58,940 --> 00:19:00,686
But what is true

398
00:19:00,710 --> 00:19:04,456
is that the very
moment... the exact, literal

399
00:19:04,480 --> 00:19:07,186
moment of my death...
someone somewhere

400
00:19:07,210 --> 00:19:08,540
will murder somebody else,

401
00:19:08,650 --> 00:19:10,526
and I haven't really
changed anything, have I?

402
00:19:10,550 --> 00:19:12,590
I haven't left anything behind.

403
00:19:13,650 --> 00:19:15,126
You've helped people, Holmes.

404
00:19:15,150 --> 00:19:17,466
You've given families
justice, peace of mind.

405
00:19:17,490 --> 00:19:19,066
Is that what I owe the world forever?

406
00:19:19,090 --> 00:19:22,090
A finger in the dam until the day I die?

407
00:19:23,460 --> 00:19:25,776
I want my choices to outlive me.

408
00:19:25,800 --> 00:19:29,276
I know that sounds... vain.

409
00:19:29,300 --> 00:19:33,000
But if I can be just a bit kinder.

410
00:19:34,310 --> 00:19:36,280
If things can be a bit more fair.

411
00:19:37,710 --> 00:19:42,196
If I can show people
something... Something beautiful

412
00:19:42,220 --> 00:19:45,326
that's been covered
under paint for decades,

413
00:19:45,350 --> 00:19:47,390
that's something, isn't it?

414
00:19:48,220 --> 00:19:50,966
"Sherlock Holmes was here."

415
00:19:50,990 --> 00:19:52,336
The older I get,

416
00:19:52,360 --> 00:19:54,560
the louder I want to
shout that into the void.

417
00:19:56,030 --> 00:19:57,230
Stupid.

418
00:19:58,100 --> 00:20:00,300
You don't have a cuffed shirt on, Holmes.

419
00:20:01,270 --> 00:20:02,716
Your left hand... you're plucking away

420
00:20:02,740 --> 00:20:05,546
at your right wrist, same
as you did yesterday.

421
00:20:05,570 --> 00:20:07,216
You're concerned about my behavior.

422
00:20:07,240 --> 00:20:09,240
I wouldn't call it behavior.

423
00:20:10,110 --> 00:20:11,216
It's more like symptoms.

424
00:20:11,240 --> 00:20:12,610
No symptoms, John.

425
00:20:12,750 --> 00:20:15,056
My priorities are shifting.

426
00:20:15,080 --> 00:20:17,256
Isn't that what friends do?

427
00:20:17,280 --> 00:20:19,250
Stand beside each other
through life's changes?

428
00:20:21,020 --> 00:20:22,566
Hobie.

429
00:20:22,590 --> 00:20:24,266
She's peeing blood, Watson.

430
00:20:24,290 --> 00:20:25,760
Calm down, hobie.

431
00:20:25,890 --> 00:20:27,566
Wendy slept through the
night. She seemed maybe,

432
00:20:27,590 --> 00:20:29,176
I don't know, like, a-a little bit better?

433
00:20:29,200 --> 00:20:30,406
And then she started
crying in the bathroom.

434
00:20:30,430 --> 00:20:31,736
She's peeing blood.

435
00:20:31,760 --> 00:20:32,876
Okay, don't panic.

436
00:20:32,900 --> 00:20:35,106
Okay, this could be anything.

437
00:20:35,130 --> 00:20:36,160
Could be benign.

438
00:20:36,270 --> 00:20:37,376
And there's no doctor here.

439
00:20:37,400 --> 00:20:38,700
We keep asking for a doctor.

440
00:20:38,810 --> 00:20:40,846
Okay, I'll be right there. Just stay calm

441
00:20:40,870 --> 00:20:42,756
and help Wendy stay calm.

442
00:20:42,780 --> 00:20:44,116
Okay.

443
00:20:44,140 --> 00:20:47,286
Not to call you out, my
friend, but whatever that is,

444
00:20:47,310 --> 00:20:49,610
it doesn't seem like
you believe it's benign.

445
00:20:49,720 --> 00:20:52,060
I think my patient's kidneys are failing.

446
00:20:57,920 --> 00:20:58,920
My kidneys are failing?

447
00:20:59,030 --> 00:21:01,166
You have hemolytic anemia.

448
00:21:01,190 --> 00:21:03,006
We're hydrating you as
aggressively as we can.

449
00:21:03,030 --> 00:21:05,976
That should help protect
your kidney function.

450
00:21:06,000 --> 00:21:07,606
You will be here for a little while, Wendy.

451
00:21:07,630 --> 00:21:09,046
Is there anyone you'd like us to call

452
00:21:09,070 --> 00:21:10,940
or anyone you think should travel?

453
00:21:11,070 --> 00:21:12,716
I should call Parker.

454
00:21:12,740 --> 00:21:16,880
She's the other paralegal
in my department. She...

455
00:21:18,040 --> 00:21:20,286
she's watching my cats.

456
00:21:20,310 --> 00:21:22,086
I'll do it.

457
00:21:22,110 --> 00:21:23,326
It'll be fine, I promise.

458
00:21:23,350 --> 00:21:24,950
- Okay. Thank you.
- Yeah.

459
00:21:26,150 --> 00:21:27,320
Anyone else?

460
00:21:28,360 --> 00:21:30,530
Do you have someone, Dr. Watson?

461
00:21:31,920 --> 00:21:34,460
Yeah, I do.

462
00:21:35,260 --> 00:21:37,076
You should go to her right now.

463
00:21:37,100 --> 00:21:39,606
Him, her, whatever.

464
00:21:39,630 --> 00:21:42,206
Wrap your arms around her.

465
00:21:42,230 --> 00:21:44,076
Time gets short really fast.

466
00:21:44,100 --> 00:21:48,000
It's Laila. She's traveling.

467
00:21:49,810 --> 00:21:52,386
But there is an underlying
cause to this, Wendy.

468
00:21:52,410 --> 00:21:54,280
You and hobie took the
same crispr treatment.

469
00:21:54,410 --> 00:21:57,856
There's a reason why it's
affecting you and not him.

470
00:21:57,880 --> 00:22:01,020
If we can figure that out,
then we can get you better.

471
00:22:01,890 --> 00:22:03,396
I hope that happens.

472
00:22:03,420 --> 00:22:05,566
Last night things seemed really good

473
00:22:05,590 --> 00:22:07,966
for the first time in a long time.

474
00:22:07,990 --> 00:22:11,606
But if something happens, if I...

475
00:22:11,630 --> 00:22:15,006
Go on dialysis, if I can't talk?

476
00:22:15,030 --> 00:22:16,500
I consented.

477
00:22:16,640 --> 00:22:18,010
I knew everything about crispr.

478
00:22:18,140 --> 00:22:19,316
I understood the risks.

479
00:22:19,340 --> 00:22:22,586
I did it because I wanted to do it.

480
00:22:24,840 --> 00:22:27,310
You have to tell people that, okay?

481
00:22:28,280 --> 00:22:31,280
You have to tell them
it wasn't hobie's fault.

482
00:22:32,690 --> 00:22:34,896
Wendy goss did not have a good night.

483
00:22:34,920 --> 00:22:37,566
I don't know how many more
bad nights she has in her.

484
00:22:37,590 --> 00:22:38,806
Who's got something for me?

485
00:22:38,830 --> 00:22:40,366
Adam and I came back to point house

486
00:22:40,390 --> 00:22:42,266
to talk to employees who
weren't here last night.

487
00:22:42,290 --> 00:22:44,506
Wendy asked a desk
clerk to send up loperamide.

488
00:22:44,530 --> 00:22:46,106
She was worried she got food poisoning

489
00:22:46,130 --> 00:22:47,576
from a French fry sandwich.

490
00:22:47,600 --> 00:22:49,176
Gi symptoms?

491
00:22:49,200 --> 00:22:50,576
We were thinking
hemolytic uremic syndrome

492
00:22:50,600 --> 00:22:51,816
caused by a shigella infection.

493
00:22:51,840 --> 00:22:53,446
She's already on antibiotics.

494
00:22:53,470 --> 00:22:55,216
If it were bacterial, her
symptoms should be improving.

495
00:22:55,240 --> 00:22:57,656
Remind him about the
chikke'en with two ks.

496
00:22:57,680 --> 00:22:58,926
Adam asked me to remind you

497
00:22:58,950 --> 00:23:00,586
about the chikke'en with two ks.

498
00:23:00,610 --> 00:23:02,996
I'm aware of the fake
chicken. If it becomes relevant,

499
00:23:03,020 --> 00:23:04,296
I'll let him know.

500
00:23:04,320 --> 00:23:05,866
We're double-checking
Wendy's samples.

501
00:23:05,890 --> 00:23:08,536
The sequencer shows
clean serum, clear targets.

502
00:23:08,560 --> 00:23:10,096
Sasha's working on a karyotype.

503
00:23:10,120 --> 00:23:11,120
And she's okay?

504
00:23:11,160 --> 00:23:12,190
She seems fine.

505
00:23:12,320 --> 00:23:13,736
She's been quiet.

506
00:23:13,760 --> 00:23:14,890
You sure about that?

507
00:23:15,030 --> 00:23:16,230
A man died yesterday

508
00:23:16,360 --> 00:23:17,836
with Sasha's picture on his nightstand.

509
00:23:17,860 --> 00:23:21,060
She keeps saying she's
fine. She wants to work.

510
00:23:21,170 --> 00:23:23,016
All right, Stephens, let
us know what comes back.

511
00:23:23,040 --> 00:23:24,800
Ingrid, tell Adam to
stick around the hotel.

512
00:23:24,900 --> 00:23:27,516
We should interview every
staffer who talked to Wendy.

513
00:23:27,540 --> 00:23:28,886
Sure. Am I not doing that, too?

514
00:23:28,910 --> 00:23:30,116
You're coming back to uhop.

515
00:23:30,140 --> 00:23:32,256
I need to see you in my office.

516
00:23:32,280 --> 00:23:34,080
Wait, am I in trouble?

517
00:23:34,210 --> 00:23:35,826
Hey.

518
00:23:35,850 --> 00:23:40,796
I am still making that list
of all your good qualities.

519
00:23:40,820 --> 00:23:42,496
Might take a minute.

520
00:23:42,520 --> 00:23:44,760
Actually, I heard back from Dr. Kim.

521
00:23:44,890 --> 00:23:46,406
She was on vacation with her family.

522
00:23:46,430 --> 00:23:48,676
Turns out she can do it, so...

523
00:23:48,700 --> 00:23:51,606
Wait, hold up. Hold up. So
I was your backup choice?

524
00:23:51,630 --> 00:23:54,976
You're busy, John. You're always busy.

525
00:23:55,000 --> 00:23:56,430
Dr. Kim is my mentor.

526
00:23:56,540 --> 00:23:58,786
Wow, so I was your fallback?

527
00:24:00,110 --> 00:24:02,816
Consider yourself off the hook.

528
00:24:02,840 --> 00:24:04,656
Look, I appreciate it.

529
00:24:04,680 --> 00:24:05,820
I really do.

530
00:24:05,950 --> 00:24:08,496
All right, wait. Hold up. I want to do it.

531
00:24:08,520 --> 00:24:10,756
Okay? Look, I'm not
gonna force my way in,

532
00:24:10,780 --> 00:24:12,156
but, yeah, I want to do it.

533
00:24:12,180 --> 00:24:15,126
So I tell you what. If you asked Dr. Kim

534
00:24:15,150 --> 00:24:17,196
because you think that
she'll give a better speech,

535
00:24:17,220 --> 00:24:18,320
I'll bow out.

536
00:24:18,460 --> 00:24:21,366
But if you think I'm too
busy or I might blow it off,

537
00:24:21,390 --> 00:24:22,736
I'm not and I won't.

538
00:24:22,760 --> 00:24:25,436
If you want the John Watson special,

539
00:24:25,460 --> 00:24:27,806
I will be there and I will deliver

540
00:24:27,830 --> 00:24:30,800
the John Watson special.

541
00:24:33,770 --> 00:24:35,246
You good?

542
00:24:35,270 --> 00:24:37,156
Yep, I should have Wendy's
karyotype ready in a second.

543
00:24:37,180 --> 00:24:39,320
No, I mean...

544
00:24:40,580 --> 00:24:42,150
are you good?

545
00:24:43,150 --> 00:24:44,590
That was awful.

546
00:24:45,420 --> 00:24:47,626
That man... uncle jun or...

547
00:24:48,990 --> 00:24:50,566
whatever we're
supposed to call him now.

548
00:24:50,590 --> 00:24:52,190
That was terrible news.

549
00:24:53,460 --> 00:24:54,706
You were kind to him.

550
00:24:54,730 --> 00:24:56,000
Even after you found out he was

551
00:24:56,130 --> 00:24:57,436
scamming you, you were still kind.

552
00:24:57,460 --> 00:24:58,806
I don't know if he was scamming me.

553
00:24:58,830 --> 00:25:01,146
He didn't ask for money. He...

554
00:25:01,170 --> 00:25:03,316
Just wanted someone in his life.

555
00:25:03,340 --> 00:25:06,610
I feel sorry for the man,
but how you treated him?

556
00:25:07,510 --> 00:25:09,880
It was better than he
had any right to expect.

557
00:25:12,850 --> 00:25:14,956
Who do you think he was?

558
00:25:14,980 --> 00:25:16,696
How did he get that baby picture of you?

559
00:25:16,720 --> 00:25:19,326
Before he came here, he worked
for the Chinese government.

560
00:25:19,350 --> 00:25:23,796
There are layers at these
international adoption agencies.

561
00:25:23,820 --> 00:25:25,096
Jun worked for one of them.

562
00:25:25,120 --> 00:25:26,706
- You never told me that.
- I didn't know.

563
00:25:26,730 --> 00:25:29,070
If it's even true, I didn't
know until this morning.

564
00:25:29,200 --> 00:25:31,676
Stephens, I got an email.

565
00:25:31,700 --> 00:25:35,576
A-Apparently, before
he died, however he died,

566
00:25:35,600 --> 00:25:37,946
jun passed my contact information along.

567
00:25:37,970 --> 00:25:39,240
Passed it to who?

568
00:25:39,370 --> 00:25:40,870
Read it for yourself.

569
00:25:41,710 --> 00:25:45,216
"Dear Sasha, my name is shu-yi."

570
00:25:45,240 --> 00:25:47,056
My god.

571
00:25:47,080 --> 00:25:48,656
Is this real?

572
00:25:48,680 --> 00:25:51,256
I don't know yet, but if it is,

573
00:25:51,280 --> 00:25:54,280
I just got a message from my birth mom.

574
00:25:55,050 --> 00:25:56,420
What do you want me to say here?

575
00:25:56,560 --> 00:26:00,806
I want your opinion. I
have this friend who has

576
00:26:00,830 --> 00:26:01,866
been behaving differently.

577
00:26:01,890 --> 00:26:04,306
It's little thing, big things.

578
00:26:04,330 --> 00:26:07,730
It all adds up to a pattern I'd call erratic.

579
00:26:07,870 --> 00:26:09,240
I'm concerned.

580
00:26:10,400 --> 00:26:12,846
Well, you're right to be worried.

581
00:26:12,870 --> 00:26:15,246
These little blank moments
in the middle of a conversation,

582
00:26:15,270 --> 00:26:17,070
they could be complex partial seizures.

583
00:26:17,180 --> 00:26:19,450
- There's no history -of epilepsy?
- No.

584
00:26:20,280 --> 00:26:24,410
The repetitive movements,
they also don't sound good.

585
00:26:24,550 --> 00:26:25,926
We call it "meaningless reaching."

586
00:26:25,950 --> 00:26:29,090
But you are John
Watson. You know all this.

587
00:26:29,220 --> 00:26:32,760
But I'm not sure that I
can be objective here.

588
00:26:33,560 --> 00:26:36,130
Tell me... tell me what
you see, Dr. Derian.

589
00:26:36,260 --> 00:26:40,060
This friend of yours, whoever he is,

590
00:26:40,170 --> 00:26:41,346
he's displaying symptoms

591
00:26:41,370 --> 00:26:42,776
that could represent a brain tumor.

592
00:26:42,800 --> 00:26:44,330
He could be very sick.

593
00:26:45,140 --> 00:26:48,086
Your friend needs to come see me.

594
00:26:48,110 --> 00:26:49,116
Today.

595
00:26:50,610 --> 00:26:53,640
Watson, we just finished
Wendy goss's karyotype.

596
00:26:53,780 --> 00:26:54,980
You need to see this.

597
00:26:55,950 --> 00:26:58,126
The karyotype on the left is
from a healthy human female.

598
00:26:58,150 --> 00:26:59,866
The chromosomes on
the right are Wendy's.

599
00:26:59,890 --> 00:27:01,060
Look at this.

600
00:27:02,890 --> 00:27:04,596
What is this?

601
00:27:04,620 --> 00:27:06,336
Half of Wendy's x
chromosomes are shattered.

602
00:27:06,360 --> 00:27:07,866
It's definitely not chemical exposure.

603
00:27:07,890 --> 00:27:09,506
We would have seen
it on the comet assay.

604
00:27:09,530 --> 00:27:11,800
Could it be a virus? Shiga toxin, maybe?

605
00:27:11,930 --> 00:27:13,406
No, it's too clean. Viral damage is messy.

606
00:27:13,430 --> 00:27:14,606
It can't be the love mod.

607
00:27:14,630 --> 00:27:15,830
She just got that yesterday.

608
00:27:15,970 --> 00:27:17,376
It's not hobie's mod,

609
00:27:17,400 --> 00:27:19,716
but it definitely looks
like crispr damage to me.

610
00:27:19,740 --> 00:27:21,046
It's the only thing that
could have shredded

611
00:27:21,070 --> 00:27:22,146
her chromosomes like this.

612
00:27:22,170 --> 00:27:24,856
The love mod was the first
time Wendy edited her genes.

613
00:27:24,880 --> 00:27:27,126
That's what she told us. She was lying.

614
00:27:27,150 --> 00:27:29,056
Wendy's used crispr before.

615
00:27:29,080 --> 00:27:31,126
She did it so often or
was so sloppy with it,

616
00:27:31,150 --> 00:27:32,690
she wrecked her own chromosomes.

617
00:27:32,820 --> 00:27:34,696
There's so much damage.

618
00:27:34,720 --> 00:27:37,320
We may not be able to help her.

619
00:27:42,160 --> 00:27:43,606
I'm sorry. I should have told you

620
00:27:43,630 --> 00:27:45,236
I hacked my genes before.

621
00:27:45,260 --> 00:27:47,730
Hobie was here. I'm sorry.

622
00:27:47,870 --> 00:27:49,070
I don't follow.

623
00:27:49,200 --> 00:27:50,876
Hobie plays with his
DNA like a rubik's cube.

624
00:27:50,900 --> 00:27:51,946
Why would he care?

625
00:27:51,970 --> 00:27:54,440
I kind of left it out at first.

626
00:27:54,570 --> 00:27:56,610
Then the more we talked,
the more excited he got

627
00:27:56,740 --> 00:27:59,556
about me doing my first mod with him.

628
00:27:59,580 --> 00:28:01,726
It was a new thing.

629
00:28:01,750 --> 00:28:03,556
I wanted it to become a real thing.

630
00:28:03,580 --> 00:28:07,096
I let hobie believe what
he wanted to believe.

631
00:28:07,120 --> 00:28:09,996
About a year ago,

632
00:28:10,020 --> 00:28:12,966
I placed three extra olfactory subvariants

633
00:28:12,990 --> 00:28:14,590
in my or3a subfamily.

634
00:28:14,730 --> 00:28:16,306
You enhanced your sense of smell?

635
00:28:16,330 --> 00:28:19,446
I have cats. They have
200 million scent receptors.

636
00:28:19,470 --> 00:28:22,176
I wanted to...

637
00:28:22,200 --> 00:28:25,470
I don't know, see what
the world is like for them.

638
00:28:26,610 --> 00:28:28,050
It's stupid.

639
00:28:29,110 --> 00:28:30,756
Are you gonna tell hobie I lied?

640
00:28:30,780 --> 00:28:33,456
No, no, that's your
job, if you want to do it.

641
00:28:33,480 --> 00:28:35,026
My job is to figure out

642
00:28:35,050 --> 00:28:37,726
why crispr damage from a
year ago has you in the icu.

643
00:28:37,750 --> 00:28:40,526
I sent him home to get some sleep.

644
00:28:40,550 --> 00:28:42,520
I'll just send him an email.

645
00:28:43,290 --> 00:28:46,136
If he doesn't want to come
back here, he doesn't have to.

646
00:28:47,890 --> 00:28:50,206
Watson, I just got back from the hotel.

647
00:28:50,230 --> 00:28:52,036
I heard about the karyotype.

648
00:28:52,060 --> 00:28:53,276
The chikke'en with two ks...

649
00:28:53,300 --> 00:28:55,046
Yes, yes, I'm aware of the chikke'en,

650
00:28:55,070 --> 00:28:56,470
and I'm aware of the two ks.

651
00:28:56,600 --> 00:28:59,570
The protein in there, they
make it with fava beans.

652
00:29:00,910 --> 00:29:02,880
Does that matter?

653
00:29:04,480 --> 00:29:07,086
The humble fava bean.

654
00:29:07,110 --> 00:29:10,656
It can trigger extreme hemolytic anemia

655
00:29:10,680 --> 00:29:14,126
like Wendy's but only
when a patient suffers from...

656
00:29:14,150 --> 00:29:15,596
A g6pd deficiency.

657
00:29:15,620 --> 00:29:20,030
When Wendy took
those passes with crispr,

658
00:29:20,160 --> 00:29:22,906
she triggered a mutation in this gene.

659
00:29:22,930 --> 00:29:24,936
You knew this?

660
00:29:24,960 --> 00:29:27,576
- You've come a long way.
- Thank you?

661
00:29:27,600 --> 00:29:29,476
Not nearly far enough, but still.

662
00:29:29,500 --> 00:29:32,816
Wendy hasn't had fava beans
since she was admitted here.

663
00:29:32,840 --> 00:29:35,540
Shouldn't the transfusions
have made a difference by now?

664
00:29:37,510 --> 00:29:38,856
The antibiotics.

665
00:29:38,880 --> 00:29:40,486
We've been trying to stave off infection.

666
00:29:40,510 --> 00:29:42,486
99% of the time, that's the right move.

667
00:29:42,510 --> 00:29:45,556
But with this mutation, it
actually makes things worse.

668
00:29:45,580 --> 00:29:47,180
We can help her.

669
00:29:47,290 --> 00:29:48,766
We can do better than that.

670
00:29:48,790 --> 00:29:51,030
Wendy's chromosomes
will be damaged forever,

671
00:29:51,160 --> 00:29:52,806
but she can live.

672
00:29:52,830 --> 00:29:54,206
We'll adjust her medications,

673
00:29:54,230 --> 00:29:56,836
and hopefully, with one last transfusion,

674
00:29:56,860 --> 00:29:58,536
she'll be back on her feet.

675
00:29:58,560 --> 00:30:00,476
She can lead a full life,

676
00:30:00,500 --> 00:30:02,606
but only if she avoids a few medications

677
00:30:02,630 --> 00:30:04,030
- and...
- Fava beans.

678
00:30:04,140 --> 00:30:05,910
Fava beans.

679
00:30:06,040 --> 00:30:07,516
Adam and Ingrid,
monitor Wendy's progress.

680
00:30:07,540 --> 00:30:09,656
Sasha and Stephens, dig into

681
00:30:09,680 --> 00:30:11,786
the backlog of our remote consults.

682
00:30:11,810 --> 00:30:13,950
We should be wrapped up here soon.

683
00:30:19,720 --> 00:30:21,466
You okay?

684
00:30:21,490 --> 00:30:24,490
Can I show you something?

685
00:30:26,890 --> 00:30:27,920
Wow.

686
00:30:28,060 --> 00:30:29,736
You're really gonna send this?

687
00:30:29,760 --> 00:30:31,006
I think I am.

688
00:30:31,030 --> 00:30:32,760
It's not crazy that she reached out.

689
00:30:32,900 --> 00:30:34,306
Jun wasn't my uncle, but he did have

690
00:30:34,330 --> 00:30:35,706
a connection to my family.

691
00:30:35,730 --> 00:30:38,576
I believe that he felt guilty for what he did

692
00:30:38,600 --> 00:30:42,216
and passed along my
information before he died.

693
00:30:42,240 --> 00:30:44,586
Look, if it's something else,

694
00:30:44,610 --> 00:30:48,086
if she asks for money or if it's a scam,

695
00:30:48,110 --> 00:30:49,310
I'll never respond again.

696
00:30:49,420 --> 00:30:53,166
I guess I just don't see a downside.

697
00:30:53,190 --> 00:30:54,460
I don't know.

698
00:30:54,590 --> 00:30:57,436
Disappointment, I guess.

699
00:30:57,460 --> 00:31:00,406
What do I have to be disappointed for?

700
00:31:00,430 --> 00:31:03,630
I'm living every dream I ever had.

701
00:31:03,760 --> 00:31:05,930
I have a family already.

702
00:31:06,070 --> 00:31:08,746
They can be annoying
as hell sometimes,

703
00:31:08,770 --> 00:31:10,046
but they ain't going anywhere.

704
00:31:11,800 --> 00:31:13,170
I have you.

705
00:31:16,780 --> 00:31:18,420
I'm gonna be fine.

706
00:31:20,010 --> 00:31:23,780
Whatever comes back,
I'm going to be great.

707
00:31:30,920 --> 00:31:33,120
I knew I'd find you here.

708
00:31:33,890 --> 00:31:36,036
Well, I'm always
happiest when I'm working.

709
00:31:36,060 --> 00:31:37,660
You know that.

710
00:31:41,970 --> 00:31:44,216
You don't believe me, do you?

711
00:31:44,240 --> 00:31:45,576
You don't believe it's under there.

712
00:31:45,600 --> 00:31:48,216
I don't think it matters.

713
00:31:48,240 --> 00:31:50,016
You're a genius, Sherlock.
I would never question that.

714
00:31:50,040 --> 00:31:53,710
But I'm... Not thinking
about what's under that paint.

715
00:31:54,810 --> 00:31:56,856
Remember Alexander Petrov?

716
00:31:56,880 --> 00:31:58,350
The cobalt fissure?

717
00:31:58,480 --> 00:32:00,096
A three-day pursuit

718
00:32:00,120 --> 00:32:01,866
chasing our quarry
across the Russian steppe?

719
00:32:01,890 --> 00:32:03,336
How could I forget that?

720
00:32:03,360 --> 00:32:06,406
Yeah, it was a three-day
pursuit that ended with us

721
00:32:06,430 --> 00:32:09,870
surrounded by soldiers
in bio hazard gear.

722
00:32:10,960 --> 00:32:13,476
I think about it all the time.

723
00:32:13,500 --> 00:32:16,676
It was three days.

724
00:32:16,700 --> 00:32:20,600
Three days exposed
to, to god knows what.

725
00:32:23,480 --> 00:32:24,816
I think you're sick, Sherlock.

726
00:32:24,840 --> 00:32:27,156
I think there's something
growing inside you.

727
00:32:27,180 --> 00:32:29,026
Everything that you've been doing...

728
00:32:29,050 --> 00:32:30,956
the faking your own death, the paranoia,

729
00:32:30,980 --> 00:32:33,480
the secrecy... you're not yourself.

730
00:32:34,990 --> 00:32:36,996
It hasn't been easy, John.

731
00:32:37,020 --> 00:32:38,696
I'm Sherlock Holmes.

732
00:32:38,720 --> 00:32:40,720
I know exactly how to solve a problem.

733
00:32:40,830 --> 00:32:43,700
I'm not afraid of a mystery.
I'm not afraid of anything.

734
00:32:44,530 --> 00:32:45,636
It hasn't been easy.

735
00:32:45,660 --> 00:32:47,776
So come on into the hospital.

736
00:32:47,800 --> 00:32:49,446
I will keep it as quiet as I can,

737
00:32:49,470 --> 00:32:52,270
but you need to see a neurologist.

738
00:32:55,810 --> 00:32:57,250
Forgive me if I'm nervous.

739
00:32:58,310 --> 00:33:01,080
It's been a while since
I've felt this exposed.

740
00:33:01,880 --> 00:33:03,980
It's right here. This room.

741
00:33:07,520 --> 00:33:10,320
So, wait here, and I'll go get Dr. Derian.

742
00:33:19,570 --> 00:33:21,770
Your numbers are looking good, Wendy.

743
00:33:21,900 --> 00:33:23,940
Transfusions are working.

744
00:33:26,770 --> 00:33:29,170
You don't seem happy.

745
00:33:30,010 --> 00:33:32,756
I haven't heard back from hobie...

746
00:33:32,780 --> 00:33:34,650
So I guess we're done.

747
00:33:35,580 --> 00:33:39,066
Okay, so you maybe
lost a potential boyfriend.

748
00:33:39,090 --> 00:33:41,360
Bummer. But you're gonna live.

749
00:33:44,820 --> 00:33:46,866
Scent receptors?

750
00:33:46,890 --> 00:33:49,260
- Cats?
- I'm sorry, hobie.

751
00:33:49,400 --> 00:33:52,406
Did you think I would
care about any of that?

752
00:33:52,430 --> 00:33:55,746
Did you think I would
care for one second?

753
00:33:55,770 --> 00:33:57,640
We'll give you two a minute.

754
00:34:01,410 --> 00:34:03,950
My god, hobie, it's working.

755
00:34:08,610 --> 00:34:09,940
I thought about what you said.

756
00:34:10,050 --> 00:34:13,096
I'm gonna end it with Beck.

757
00:34:13,120 --> 00:34:14,990
I think that's a good idea.

758
00:34:15,820 --> 00:34:17,596
I appreciate you taking my advice.

759
00:34:17,620 --> 00:34:20,520
I thought about what you said.

760
00:34:20,630 --> 00:34:24,236
And when you get down
to it, penises abound.

761
00:34:25,360 --> 00:34:26,836
Yeah, I guess they do.

762
00:34:26,860 --> 00:34:28,576
And you have to sort
through a pile to find the one

763
00:34:28,600 --> 00:34:32,676
that does what it's supposed
to, but penises abound.

764
00:34:34,270 --> 00:34:35,400
Watson?

765
00:34:35,510 --> 00:34:37,116
- Everything okay?
- I need your help.

766
00:34:37,140 --> 00:34:39,510
I need your help.

767
00:34:40,350 --> 00:34:42,326
I kissed her. A-All I did was kiss her.

768
00:34:42,350 --> 00:34:43,456
We need some help in here.

769
00:34:43,480 --> 00:34:44,856
What is happening?

770
00:34:44,880 --> 00:34:46,126
Let's get her on some oxygen.

771
00:34:46,150 --> 00:34:48,050
What happened?
What-what-what did I do?

772
00:34:48,920 --> 00:34:50,520
What did I do?

773
00:34:56,360 --> 00:34:58,036
- What happened, hobie?
- I already told you.

774
00:34:58,060 --> 00:34:59,676
- I kissed her. That's it.
- The tattoo on Wendy's forearm.

775
00:34:59,700 --> 00:35:01,006
It glowed. It didn't before,

776
00:35:01,030 --> 00:35:02,576
but right before you kissed, it did.

777
00:35:02,600 --> 00:35:03,846
- Does that matter?
- I thought that just meant

778
00:35:03,870 --> 00:35:05,510
she didn't love me until now.

779
00:35:07,040 --> 00:35:08,180
Watson.

780
00:35:09,210 --> 00:35:10,810
Does that matter?

781
00:35:12,340 --> 00:35:15,110
Wendy's inflammation
inhibited her flow of oxytocin.

782
00:35:15,250 --> 00:35:17,396
When we stopped
triggering her with antibiotics,

783
00:35:17,420 --> 00:35:18,996
her love hormone could flow freely.

784
00:35:19,020 --> 00:35:21,426
That explains the glowing,
but what's wrong with her?

785
00:35:21,450 --> 00:35:24,066
I think we have uncovered a new allergy.

786
00:35:24,090 --> 00:35:25,336
We're gonna be fine.

787
00:35:25,360 --> 00:35:28,960
Wendy's gonna stabilize,
we'll reverse her love mod...

788
00:35:29,700 --> 00:35:31,406
and she's-she's gonna be fine.

789
00:35:31,430 --> 00:35:32,830
Okay.

790
00:35:34,530 --> 00:35:39,346
If Wendy's gonna be fine,
then why do you look so sad?

791
00:35:39,370 --> 00:35:40,686
We fixed Wendy's response

792
00:35:40,710 --> 00:35:42,486
to the fake chicken with the fava beans.

793
00:35:42,510 --> 00:35:45,186
Now that her oxytocin's flowing freely,

794
00:35:45,210 --> 00:35:46,656
she's having a reaction to the tattoo's

795
00:35:46,680 --> 00:35:48,586
bioluminescence proteins.

796
00:35:48,610 --> 00:35:52,426
Like I said, we have to reverse
the love mod that you gave her.

797
00:35:52,450 --> 00:35:53,780
Great.

798
00:35:53,920 --> 00:35:56,096
I... how is that not great?

799
00:35:56,120 --> 00:35:57,696
Your chest, hobie.

800
00:35:57,720 --> 00:36:00,966
You. You're filled with the same proteins.

801
00:36:00,990 --> 00:36:05,306
Wendy's not just allergic to the tattoos.

802
00:36:05,330 --> 00:36:06,560
She's allergic to you.

803
00:36:06,670 --> 00:36:08,640
You can't be around her. You will kill her.

804
00:36:08,770 --> 00:36:10,816
So, reverse it. Take away my glow.

805
00:36:10,840 --> 00:36:12,446
- Who cares?
- You know I can't do that.

806
00:36:12,470 --> 00:36:14,286
You've been playing god with
your own genome for years.

807
00:36:14,310 --> 00:36:17,010
I mean, to walk all that back...

808
00:36:17,140 --> 00:36:20,386
The number of genes
that we'd have to open up...

809
00:36:20,410 --> 00:36:22,126
There's no map.

810
00:36:22,150 --> 00:36:24,226
You'd experience genomic instability...

811
00:36:24,250 --> 00:36:26,850
Off-target mutations.

812
00:36:26,990 --> 00:36:28,896
You'd probably die.

813
00:36:28,920 --> 00:36:30,466
I'm not gonna help you do that.

814
00:36:30,490 --> 00:36:31,766
Watson.

815
00:36:31,790 --> 00:36:33,490
We've got her stable.

816
00:36:34,260 --> 00:36:35,836
I'm sorry, hobie.

817
00:36:35,860 --> 00:36:39,200
Wendy's gonna live. You're gonna live.

818
00:36:41,270 --> 00:36:42,970
You just can't be together.

819
00:36:58,450 --> 00:37:01,196
You wanted to see me, guv?

820
00:37:01,220 --> 00:37:03,420
He's alive, shinwell.

821
00:37:04,490 --> 00:37:07,090
Holmes. He's alive.

822
00:37:09,300 --> 00:37:10,630
Wow.

823
00:37:11,430 --> 00:37:13,730
"The Pittsburgh mystery."

824
00:37:13,870 --> 00:37:15,910
Holmes mentioned this.

825
00:37:16,700 --> 00:37:19,316
I was meant to keep it secret.

826
00:37:19,340 --> 00:37:21,910
I've had me suspicions, guv.

827
00:37:22,040 --> 00:37:24,656
Ever since you first used that phrase,

828
00:37:24,680 --> 00:37:26,786
- I've had me suspicions.
- No.

829
00:37:26,810 --> 00:37:28,950
Holmes is sick.

830
00:37:31,050 --> 00:37:33,250
I think he's very, very sick.

831
00:37:34,350 --> 00:37:36,420
We have to find him, shinwell.

832
00:38:02,510 --> 00:38:03,910
- Hobie.
- Hey.

833
00:38:04,050 --> 00:38:05,850
What are you doing?
You can't be here, hobie.

834
00:38:05,880 --> 00:38:08,996
Maybe not yesterday, but
today I'm right where I need to be.

835
00:38:09,020 --> 00:38:11,066
Wendy, can I show you something?

836
00:38:11,090 --> 00:38:15,236
Just give me 30 seconds,
and if you want me to go,

837
00:38:15,260 --> 00:38:16,630
I'll go.

838
00:38:17,700 --> 00:38:19,600
You did it to yourself.

839
00:38:19,730 --> 00:38:22,046
- You've reversed your mods.
- What's the matter

840
00:38:22,070 --> 00:38:23,246
with you, hobie? You could have died.

841
00:38:23,270 --> 00:38:24,776
- You still could.
- Why?

842
00:38:24,800 --> 00:38:26,230
Why would you do that?

843
00:38:26,340 --> 00:38:28,486
You're the man with the glowing chest.

844
00:38:28,510 --> 00:38:31,116
No. That's not true.

845
00:38:31,140 --> 00:38:35,610
The only reason I ever glowed
was so that you could find me.

846
00:38:39,620 --> 00:38:41,290
You are here now.

847
00:38:41,420 --> 00:38:44,320
The technology's obsolete.

848
00:38:45,260 --> 00:38:46,900
Hobie.

849
00:38:48,160 --> 00:38:50,660
I know things got crazy here today.

850
00:38:50,800 --> 00:38:52,976
I'm letting you off the hook.

851
00:38:53,000 --> 00:38:54,900
I wrote it.

852
00:38:59,340 --> 00:39:03,010
I told you I was gonna do it, so I did it.

853
00:39:11,150 --> 00:39:12,320
Thank you.

854
00:39:25,460 --> 00:39:26,830
This isn't a good idea.

855
00:39:26,970 --> 00:39:29,076
- Hi.
- Don't interrupt.

856
00:39:29,100 --> 00:39:30,740
This isn't a good idea.

857
00:39:31,700 --> 00:39:34,370
You're not a good idea.

858
00:39:35,440 --> 00:39:36,770
Okay.

859
00:39:37,680 --> 00:39:38,716
"Okay"?

860
00:39:38,740 --> 00:39:40,370
We're two bad people, Ingrid.

861
00:39:40,510 --> 00:39:42,326
Two bad people doing a
good thing for each other.

862
00:39:42,350 --> 00:39:46,226
But if it's not working for you anymore...

863
00:39:46,250 --> 00:39:48,196
I get it. I'm good.

864
00:39:48,220 --> 00:39:49,636
If you change your mind, that's okay, too.

865
00:39:49,660 --> 00:39:50,936
You know where to find me.

866
00:39:54,290 --> 00:39:56,190
I expected...

867
00:39:56,330 --> 00:40:00,200
I don't know, a-a fight,
a scene. Something.

868
00:40:02,530 --> 00:40:04,200
It's okay.

869
00:40:07,370 --> 00:40:09,870
Well, therapy is about to start.

870
00:40:10,010 --> 00:40:11,616
Yeah, I'll be in in a few.

871
00:40:11,640 --> 00:40:13,386
I just got to finish this.

872
00:40:34,230 --> 00:40:38,130
I can't believe it, and
you're incredibly lucky,

873
00:40:38,240 --> 00:40:40,010
but you're doing just fine.

874
00:40:40,740 --> 00:40:43,456
That was really stupid, by the way.

875
00:40:43,480 --> 00:40:44,950
I know that.

876
00:40:45,080 --> 00:40:47,326
Of course I know that.

877
00:40:48,550 --> 00:40:51,596
Your... girlfriend. Laila, right?

878
00:40:51,620 --> 00:40:54,266
- Is she back in town?
- Yeah, I saw her last night.

879
00:40:54,290 --> 00:40:56,636
And yet something tells me

880
00:40:56,660 --> 00:40:59,330
you still haven't done the deed.

881
00:41:01,430 --> 00:41:03,676
We're grown-ups, hobie. Of
course we've done the deed.

882
00:41:03,700 --> 00:41:05,506
No, I'm not talking about sex.

883
00:41:05,530 --> 00:41:08,446
Have you told your girlfriend
that you love her yet?

884
00:41:08,470 --> 00:41:10,276
Again, we're grown-ups.

885
00:41:10,300 --> 00:41:12,346
We're doing things at a grown-up pace.

886
00:41:12,370 --> 00:41:15,086
You're a smart man, John Watson,

887
00:41:15,110 --> 00:41:17,086
so I'm sorry for saying this, but...

888
00:41:17,110 --> 00:41:19,950
You can be a real idiot sometimes.

889
00:41:22,980 --> 00:41:25,256
Life is hard.

890
00:41:25,280 --> 00:41:29,620
It's hard and it's confusing and it's lonely.

891
00:41:29,760 --> 00:41:33,766
And we all live in the
middle of that, and sometimes

892
00:41:33,790 --> 00:41:37,806
we are lucky enough
to find someone to love.

893
00:41:37,830 --> 00:41:43,146
To have someone
who might love us back.

894
00:41:43,170 --> 00:41:48,000
And if you've got that,
it's not time to be smart.

895
00:41:48,140 --> 00:41:51,510
It's not time to be a grown-up.

896
00:41:52,340 --> 00:41:55,286
If you're not willing to lay
yourself on the line for love,

897
00:41:55,310 --> 00:41:57,810
if you're not willing to be stupid,

898
00:41:57,950 --> 00:42:00,650
then why do you even
deserve love in the first place?

899
00:42:00,790 --> 00:42:05,390
Now, I'm glad I am doing better...

900
00:42:06,260 --> 00:42:08,466
but I think you should go now

901
00:42:08,490 --> 00:42:10,806
and find the woman you love,

902
00:42:10,830 --> 00:42:13,406
and I think you should tell her all about it.

903
00:42:23,710 --> 00:42:26,056
- Hey, is she in?
- Conference room, but she's in a meeting.

904
00:42:26,080 --> 00:42:27,650
Sorry, this can't wait anymore.

905
00:42:37,890 --> 00:42:40,060
John. What are you doing?

906
00:42:40,190 --> 00:42:43,206
Captioning sponsored by

907
00:42:43,230 --> 00:42:46,370
captioned by media access
group at wgbh access.Wgbh.Org

